Editor-in-Chief Ufuk Demirkılıç Frequency Quarterly Abbreviation Turk J Vasc Surg Publisher Turkish National Vascular and Endovascular Surgery Society ISSN 2667-4947 E-ISSN 2667-5080

Turkish Journal of Vascular Surgery 2012 , Vol 21 , Issue 3
Lemierre Syndrome: Case Report
1Departments of Cardiovascular Surgery, Ankara Dışkapı Yıldırım Beyazıt
2Department of General Surgery, Ankara University Faculty of Medicine, Ankara
3Departments of Radiyology, Ankara Dışkapı Yıldırım Beyazıt Education and Research Hospital
DOI : 10.9739/uvcd.2012-31357 Lemierre syndrome (LS) is a very rare disease presenting with thrombosis of internal juguler vein (IJV) and septic embolia following orophrangeal infection. The common complaint in LS is pain in the throat and the usual findings are unilateral swelling and decrease in range of mo- tion of neck. For diagnosis, Doppler ultrasonography can be used. The case presented here is 29 ye- ars old healthy multipar woman. In this case, following postphrangial infection, thrombosis of the right IJV and partial thrombosis of internal carotid artery (İCA) were found. The laboratory findings of the case revealed high homosistein levels and mutation in the metilentetrahidrofolat (MTHFR) 677 CT and MTHFR 1298AC genotype. Moreover, the other laboratory findings confirmed anti- phospholipid syndrome (APS). The patient was treated with antibiotics and anticoagulants. Due to repetation of the postphrangial infection this case is LS, a very rare cause of thrombosis with ac- companying hereditary trombophilia mutations and APS . The patient was suggested to keep away from infections and continue taking anticoagulants and stop taking contraceptive pills. Keywords : Thrombophilia; Lemierre syndrome; thrombosis; polymorphism
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