Editor-in-Chief Ufuk Demirkılıç Frequency Quarterly Abbreviation Turk J Vasc Surg Publisher Turkish National Vascular and Endovascular Surgery Society E-ISSN 2667-5080

Turkish Journal of Vascular Surgery 2016 , Vol 25 , Issue 3
The Efficacy and Safety of Pharmacomechanical Thrombolysis and Medical Therapy for Symptomatic Deep Venous Thrombosis
Erdinç EROĞLU1, Murat ARI2
1Department of Cardiovascular Surgery, Kahramanmaraş Sütçü İmam University Faculty of Medicine, Kahramanmaraş
2Clinic of Cardiovascular Surgery, Gaziantep State Hospital, Gaziantep
DOI : 10.9739/uvcd.2017-57077 Objective: To prospectively compare the efficacy and safety of pharmacomechanical thrombolysis (PMT) and medical therapy for symptomatic deep venous thrombosis (DVT). Material and Methods: Between January 2015 and July 2016, 69 patients with a history of lower extremity DVT symptoms less than 21 days were managed either with a rotational thrombectomy device (ReyaThrombectomy ® Biolas FG Grup, Ankara, Turkey) or medical therapy including anticoagulation and compression stocking. Degree of lysis, symptomatic relief and patency were analyzed. Results: Thirty-four (47.9.0%) of the patients had a ilio-femoral thrombosis. The mean duration of the symptoms was 6.8 (2-20) days. Fourty-four and twenty-five patients were managed with PMT and medical therapy, respectively. At the end of the PMT procedure, 36 patients (81.8%) had a complete (Grade III) thrombus resolution. Grade II lysis was noted in 8 (18.2%) of the patients. One patient developed access site hematoma. There was no mortality. At third month, the venous obstruction was observed in 7 (15.9%) and 11 (44%) of patients in PMT and medical therapy groups, respectively (p<0.05). There was a significant clinical improvement in PMT group as evaluated by clinical symptom score. (1.6±0.8 vs. 2.1±0.8, p=0.02). Conclusion: The rotational thrombectomy is safe, fast and more effective alternative to current medical therapy for the management of DVT. Keywords : Deep venous thrombosis; rotational thrombectomy
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