Editor-in-Chief Ufuk Demirkılıç Frequency Quarterly Abbreviation Turk J Vasc Surg Publisher Turkish National Vascular and Endovascular Surgery Society E-ISSN 2667-5080

Turkish Journal of Vascular Surgery 2022 , Vol 31 , Issue 2
The relationship between platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio and prognosis in carotid artery endarterectomy
Tolga Bas1, Deniz Çevirme1, Hakan Hançer1, Rezan Aksoy1, Ahmet Zengin1, Baburhan Özbek2, Kaan Kırali1
1Kartal Koşuyolu High Speciality Training and Research Hospital, Cardiovasculary Surgery, İstanbul, Türkiye
2Kartal Koşuyolu High Speciality Training and Research Hospital, Pediatric Cardiovasculary Surgery, İstanbul, Türkiye
DOI : 10.9739/tjvs.2022.1143 Objectives: In this study, we aimed to analyze the effect of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) on prognosis during one-year follow-up after carotid endarterectomy surgery.

Patients and methods: Between October 2012 and December 2019, a total of 250 patients (176 males, 74 females; mean age: 67.7±8.8 years; range, 47 to 94 years) with isolated carotid artery endarterectomies were retrospectively analyzed. All patients" data were obtained from the hospital information management system and hospital archive. The patients were divided into two groups (Group 1, n=232 and Group 2, n=18) according to the one-year mortality rate and the risk factors were analyzed.

Results: During follow-up, the one-year mortality and one-year no mortality groups were compared. Univariate model revealed that there were statistically significant differences between the groups regarding congestive heart failure, platelet count, NLR, and neurological complications (p<0.05). Additionally, the multivariate model indicated that congestive heart failure, NLR, and neurological complications were statistically different between the groups (p<0.05).

Conclusion: Inflammatory and oxidative stress agents play an important role in the prognosis of cardiovascular diseases. The NLR and PLR may be helpful in understanding carotid artery disease and stroke. The NLR levels, preoperative congestive heart failure, and neurological complications in the early postoperative period seem to be the most important prognostic criteria in terms of mortality during one-year follow-up. Keywords : Carotid artery endarterectomy, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio

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