The Effects of Clostridıopeptidase A on Venous Ulcers

In this study 20 patients with venous ulceration were assigned into two groups. in the first group, elastic com­ pression and wet draping were used and in the other group clostridiopeptidase A with elastic compression were used and the healing effect of clostridiopeptidase A on venous ulcers were evaluated.

In the elastic compression and wet draping group, 8 of the 1O ulcers were healed during the study period of up to 6 months (mean 151.5). in 2 patients venous ulcers were persisted by the end of the study. in the elastic com­ pression and clostridiopeptidase A group, complete healing of all ulcers were observed during the study period (mean 103.5, p 0.05).

Specific affinity tor natural collagen and painless debridement makes the clostiridiopeptidase A and elastic co­ pression combination an effective therapeutic modality in venous ulcers.