Effect of curcumin on erythrocyte deformability in mice with limb ischemia-reperfusion injury
Gökhan Arslan, Hakan Kartal, Faruk Metin Çomu, Erdem Çetin, Hüseyin Sicim, Ertan Demirdaş, Celalettin Günay, Bilgehan Savaş Öz
DOI: 10.9739/tjvs.2022.1104 · Page: 33-38 · 83 Views · 3 Downloads · 0 Citations
Abstract
Results: There was a statistically significant difference in the mean deformability index among the groups. The IR group (2.1±0.3) significantly higher than the mean of control group (1.6±0.2), CUR group (1.6±0.1) and DMSO group (1.6±0.2). The deformability index values of the IR/CUR group approach the control group through the application of the curcumin (1.8±0.2).
Conclusion: Our study showed negative effects of IR on erythrocyte deformability in mice. Also, curcumin had positive effects by reversing the undesirable effects of IR.Keywords : Curcumin, erythrocyte deformability, ischemia-reperfusion
Keywords : Curcumin; erythrocyte deformability; ischemia-reperfusion