THE EFFECTS OF PERIPHERAL NUTRITION SOLUTION TO PREVENT INFUSION THROMBOPHLEBmS

Not only the factors belonging to veins and catheters, the pH, osmolarity and the composition of the solution are very important to prevent infusion thrombophlebitis which is one of the most important complications during peripheral parerıterall nutrition (PPN) . The aim of this clinical study is to investigate the influence of the solution with or without lipid content to the infusion thrombophlebiti s. The patients were divided into two groups. The solutions with the contents of glucose, aminoacid, electrolyte were given to the first group which included 15 patients . To the second group of 15 patients the solution with the contents of glucose, amin oacid, electrolyte and lipid were given. The infusion sites were evaluated for the risk of thrombophlebitis and they were scored according to Maddox classification. Maddox score medians of the thrombophlebitis in group il patients are signifi cantly lower than group I patients (p< 0.05). The PPN were abandoned in the 3 patients in the first group because of thrombop'lıiebiti s.

The parenteral nutrition solutions with lipid content may prevent thrombophlebitis by protecting effects on the vascular erıdothelium of peripheral veins independent from the pH and osmolarity of the solutions.