The effect of mean platelet volume-to-lymphocyte ratio on symptom onset in patients with carotid artery stenosis

Results: The mean age was 53.6±8.5 years in Group 1 and 64.9±9.7 years in Group 2 (p<0.001). In the multivariate analysis, advanced age (odds ratio [OR]: 1.235, 95% confidence interval [CI]: 1.204-1.738, p=0.012), hypertension (OR: 1.030, 95% CI: 1.007-1.552, p=0.037), and MPVLR (OR: 2.156, 95% CI: 1.932-3.116, p=0.005) were found to be independent predictors of the symptom onset. The receiver operating characteristics analysis revealed that the cut-off value for MPVLR was 5.48 (area under the curve [AUC]=0.694, 95% CI: 0.563-0.806, p=0.008) with 69.7% sensitivity and 51.2% specificity.

Conclusion: Our study results show that the high MPVLR value, which is a cheap parameter that can be calculated easily, can be used as a promising parameter of CAS symptoms for clinicians.

Keywords : Carotid artery stenosis, cerebrovascular event, lymphocyte, mean platelet volume