Year : 2021, Volume : 30, Issue : 2

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Vascular endothelium protective property of curcumin

Serdar Bayrak, Gizem Çalıbaşı-Koçal, Feriha Toksöz, Tuğra Gençpınar, Nazlı Mert Özüpek, Asuman Feda Bayrak, Ezgi Daşkın, Yasemin Başbınar

DOI: 10.9739/tjvs.2021.927 · Page: 121-126 · 100 Views · 12 Downloads · 1 Citations

Abstract

Results: The 1.77 μM of curcumin increased the cell viability by 150% after 48 h of treatment. According to the wound healing results, after 48 h of incubation, the control group and 1.77 μM curcumin exhibited 47.1% and 43.8% closure, respectively. The mean maximum and minimum tube lengths were found to be 21,858±3,945 and 12,438±3,817 pixel for curcumin, respectively with low fetal bovine serum (FBS) and curcumin with high FBS, respectively.

Conclusion: Our results show that curcumin is a promising endothelial protective agent for HUVEC cell line.

Keywords : Curcumin, cytotoxic effect, endothelium protective, wound healing

Keywords : Curcumin; cytotoxic effect; endothelium protective; wound healing

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